As per the definition of American Chemical Society, “Biotech/Biotechnology is the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials and organisms such as pharmaceuticals, crops, and livestock.”
And, the European Federation of Biotechnology defines biotechnology as “the integration of natural science and organisms, cells, parts thereof, and molecular analogues for products and services.”
Basic biological sciences (e.g. molecular biology, biochemistry, cell biology, embryology, genetics, microbiology) is the basis of Biotechnology and conversely provides methods to support and perform basic research in biology.
With modernization and more R&D, Biotech is a field to explore. Hence, here we provide Top 10 Biotechnology Companies In India In 2021-
1) Xcode Life Sciences
Founded in 2010, by Saleem Mohammed, Abdur Rub, Naru Narayanan, Xcode Life is a personal genomics company. This startup is exceptionally outstanding in personal genomics, and specializing in preventative healthcare.
This startup aims to empower physicians, wellness professionals and individuals with the most authenticated and trustable actionable genomic information to improve the quality of life and impact it positively. Using advances in genomics, informatics, computing, and domain-specific knowledge, Xcode is working towards making personalised experiences for clients across clinical and non-clinical segments.
As per Crunchbase, Xcode Life science methodology is to opt for genetic tests that are performed using saliva screens for the presence or absence of the mutations through a technique called genotyping. In the genetic reports, the information about genotype and its associations for specific conditions are furnished.
The protocols and equipment that are used are world-class, and the procedure and method of testing are in line with international standards. As per Xcode Life Sciences, “Xcode Life reports are compatible with more than 50 raw data formats including 23andMe, AncestryDNA, Family Tree DNA (FTDNA), Living DNA, My Heritage DNA, and whole-genome sequencing files”.
2) OncoStem Diagnostics Pvt. Ltd.
Founded in 2011 by Manjiri Bakre, this Bangalore based biotechnology startup OncoStem works to develop innovative tests to personalize treatment for cancer patients. Their understanding of tumour biology helps physicians in optimizing therapy for cancer patients. Their highly innovative multi-marker test identifies patterns of recurrence amongst cancer patients.
An understanding of these patterns ensures that patients receive personalized therapies and treatments that are best suited to their condition. This startup aims to develop the latest technology to facilitate personalized cancer treatment, thus improving the quality of life for cancer patients.
Their flagship product CanAssist Breast was launched for hormone-positive breast cancer. In this, they classify the patients as ‘low-risk or ‘high-risk’ based on the patient’s risk of a breast cancer recurrence over the time of five years.
CanAssist Breast furnishes the required information on the risk of recurrence of early-stage, hormone-receptor-positive breast cancer patients. This helps oncologists in personalizing treatment plans. This biotech startup is also working on similar tests for other cancer types including triple-negative breast cancer and ovarian cancer.
3)Pandorum Technologies Pvt. Ltd.
Founded in 2011 by academic entrepreneurs Tuhin Bhowmick, and Arun Chandru, Pandorum Technologies Pvt. Ltd. is a Bangalore based biotechnology startup that works on tissue engineering and regenerative medicine. With its distinct team, working in the field of life science, engineering and clinical competencies, the startup designs and manufactures 3-D functional human tissues; meant for medical research and therapeutics.
Pandorum Technologies is backed by esteemed investors like the Biotechnology Industry Research Assistance Council, Department of Biotechnology, GoI. Pandorum’s labs, National Centre for Biological Sciences campus, Bengaluru, and in the Bangalore Bioinnovation Centre, Biotech Park, Electronics City Phase 1, Bengaluru.
This biotech startup develops and disseminates high-end innovations addressing the most important challenges in healthcare.
In 2013, MedGenomes was founded by Sam Santosh. It provides personalised genetic tests and medicines for several ailments like cancer, diabetes and neurological illness. The Company has headquarters in the U.S.A. and India.
For molecular genetic diagnostic tests, MedGenomes uses Sanger sequencing and next-generation sequencing technologies for treatment. The company has various tests done through exome, whole genome, and mitochondrial genome sequencing.
It also services like hereditary cancer panels for testing mutations in genes responsible for multiple hereditary cancer syndromes; tests to detect changes in the DNA of tumour cells in the tumour somatic mutation panel; genetic testing for several types of cardiac, eye, and neuromuscular diseases; targeted panels to test for mutations in genes implicated in causing autosomal recessive and dominant forms of non-syndromic deafness, and autism panels for investigation of genes to influence disorders within the autism spectrum.
Founded by Anuradha Acharya in 2012, MapMyGenome is a molecular diagnostics startup that aims to make people proactive about their health. This Hyderabad based startup offers personalized health solutions based on genetic tests that help their customers to know about themselves.
By integrating genetic health profiles and health histories with genetic counselling, Mapmygenome gives actionable steps for patients and their physicians on a journey of healthy living. Mapmygenome provides preventive health care through healthy habits. Personal Genomics, Molecular Diagnostics, DNA Forensics and Brain Wellness are their key products and services.
6) Sea6 Energy
The company was founded in 2010 by IIT Madras students namely Sailaja Nori, Nelson Vadasseri, Sayash Kumar, Sowmya Balendiran and their professor Shrikumar Suryanarayan.
Sea6 has managed to harness seaweed grown in Oceans so that the company utilises it in creating a wide range of bioproducts to enhance plant and animal immunity to boost agriculture and provide an alternate source of energy. It has raised about a total funding amount of ₹8.9 million. It is headquartered in Bengaluru, India.
7) Zumutor Biologics
Zumutor Biologics, founded in 2013 by Kavitha Iyer Rodrigues, is a leading startup in immune-oncology in NK Cell therapeutics. It helps treat cancer by targeting the body’s immune system.
It is headquartered in CIC Cambridge Campus, MA and R&D is carried out at an ISO certified lab in Bangalore, India. It has raised more than ₹41.6 million in total funding.
8) Farcast Biosciences
Founded in 2010 by Pradip K. Majumder & Mallikarjun Sundaram, Farcast Biosciences, erstwhile known as Mitra Biotech. In 2019, they renamed themselves Farcast Biosciences.
Farcast Biosciences is a cancer diagnostic research company committing its efforts towards elucidating the tumour micro-environment and associated immune compartment components. This startup developed its flagship platform, CANScript, which aids oncologists to identify which drug will give the most optimised and suitable results.
They are the pioneers of human tumour histoculture science and are persistently invested in learning and navigating the complex field of recreating near-native human Tumor immune MicroEnvironment (TiME) ex vivo.
Setup in 2014, Bugworks is incubated in C-CAMP, Bangalore. The core scientiﬁc team of this startup has combined experience of over 200 years in Infection Drug Discovery. Bugworks engages with several globally reputed partners to pitch and project its breakthrough broad spectrum assets.
It works on the approach of Anti-bacterial lead generation that has largely been hindered by the presence of eﬄux pumps. Bugworks has employed a strategy ELUDE to evade eﬄux pumps. ELUDE provides multiple leads that are powerful against Gram-negative and Gram-positive bacteria.
10) GANIT Labs
Founded in 2010 and headquartered in Bangalore, Ganit Labs is a genome sequencing and translational genomics lab. It uses second-generation sequencing instruments, computes clusters and human brains to sequence, analyzes and interpret genome data from a variety of organisms.
It’s a not-for-profit, Government-funded, public-private partnership initiative in the area of functional genomics and next-generation sequencing.
The company aims to solve fundamental scientific problems by experimenting with the help of real-time PCR, DNA microarray and next-generation sequencing equipment, and analyzing and interpreting high-throughput data retrieved from these instruments.